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Commercial Real Estate for Sale in Upstate SC

Commercial activity in the Upstate follows the interstates. I-85 between Greenville and Spartanburg carries the industrial and distribution demand, with BMW and its supplier network anchoring most of it; retail and office concentrate around the two downtowns and the Highway 9 and Fairview Road corridors.

Commercial runs on different diligence than residential — zoning and permitted use, environmental history, existing leases and their remaining terms, and what a building can actually be converted to. Tell us what you are trying to do and we will scope the search.

Commercial Listings

1201 N Fant Street Unit A&B, Anderson
$329,900
20309243 MLS
HIGH-VISIBILITY COMMERCIAL OFFICE NEAR ANMED — APPROXIMATELY 10,700 VEHICLES PER DAY! Discover a renovated, move-in-ready professional office at 1201 N. Fant Street in Anderson, SC. Set along a four-lane corridor near AnMed Medical Center, this approximately 1,467-SF, single-story building on a 0.27-acre lot offers road exposure, convenient access, and flexibility for owner-occupants or investors. Originally built as a duplex in the 1960s, the property has been extensively renovated and combined into one professional office. Formerly used as a spa and most recently by The Alliances Business Solutions, it offers an adaptable layout for a range of professional services. INTERIOR & IMPROVEMENTS: Attractive paint finishes, upgraded lighting, Cat 5 wiring, replacement windows installed approximately 10 years ago, and a new HVAC system. The layout features reception space potentially adaptable to two reception areas; two conference rooms or offices with French doors opening to reception; two spacious private offices; two break rooms; and two storage vestibules. Laundry hookups and a bathroom with a bathtub provide added functionality for certain uses. PRIME N. FANT STREET LOCATION: Close to AnMed Medical Center, medical practices, and established professional offices. SCDOT reports approximately 10,700 vehicles daily (2024 AADT) on a nearby N. Fant Street segment. This visibility offers a small professional practice a recognizable business location without requiring a large commercial footprint. Signage and uses are subject to applicable approvals. POSSIBLE USES: Accounting, legal, financial planning, insurance, consulting, real estate, counseling, wellness, spa, and other professional offices. Healthcare-related uses may be possible, subject to zoning, permits, accessibility, and occupancy requirements. INVESTMENT POTENTIAL: An option for an owner-occupied headquarters or a commercial rental investment. Its renovated office layout and location near AnMed may appeal to prospective tenants. The original duplex configuration may warrant investigation of future multi-tenant use, subject to code, zoning, parking, utility, and improvement requirements. Rental income and returns are not guaranteed. Schedule a private tour of 1201 N. Fant Street and explore the possibilities for your business or investment portfolio! BUYER NOTICE: MLS information is believed accurate but not guaranteed. Buyers and their representatives should cross-check this description against all MLS supplements, disclosures, and documents and independently verify square footage, acreage, measurements, systems, improvements, condition, zoning, permitted uses, traffic counts, and all other material information before closing. Any rental or investment projections are estimates only.

1201 N Fant Street Unit A&B, Anderson

54 & 60 Paul Bridges  Road, Alexander
$996,400
4439873 MLS
Enjoy a rare blend of private pond-front living, custom craftsmanship, pastoral scenery, and versatile possibilities. This completely custom-built, approximately 1,700-square-foot cottage overlooks a private, stocked pond and features two bedrooms, plus a bedroom-sized bonus room attached to the main-level primary bedroom. Inside, find warm wood flooring, shiplap walls, built-ins, exposed beams, and brick fireplaces on both the main and walkout basement levels. The primary suite includes a clawfoot soaking tub, while a second, fully functioning tub on the private back deck offers a distinctive place to unwind. Covered outdoor spaces on both levels extend the living area, with a covered main-level deck and a covered basement patio. Enjoy the water from the screened-in dock house, covered and open dock areas, or the spacious waterfront fire pit and dedicated sitting area. The cottage’s setting takes in pastoral and mountain views, with adjacent farmland protected by an agricultural conservation easement to help preserve the pastoral surroundings. A separate event building offers approximately 1,400 square feet of heated and cooled interior space with over 1,700 square feet of covered patio/gathering area. Features include a striking stone fireplace, rollup bay doors, a 10-foot brick entry, brick sidewalks, and a flagstone patio in front of a detached bar area. Previously operated as a wedding venue, the building offers potential for a range of uses, including events, boutique retail, professional offices, brewery, a private entertainment retreat, or a short-term rental. With a custom two-bedroom cottage, bonus room, stocked pond, screened dock house, outdoor gathering spaces, protected pastoral views, and adaptable event venue, this distinctive property invites buyers to consider a private residence, vacation retreat, or investment opportunity. Take a Virtual Tour of the cottage here: https://my.matterport.com/show/?m=BPDjEJVHoK8& and see the Property Video here: https://listings.wncrealestatephotography.com/videos/01a1c600-5845-726d-94c3-946ac7c438fd

54 & 60 Paul Bridges Road, Alexander

Easley
$512,000
343655 MLS
Small-Town Charm, BIG Business Potential! 2,316 SF Commercial Property | Retail | Restaurant | Coffee Shop | Country Store A Little Country Charm with Endless Possibilities! Looking for a unique commercial property with character, charm, and opportunity? This 2,316-square-foot retail property offers the perfect blend of small-town charm and modern improvements! An Exciting New Chapter for Hive & Garden Country Store! Hive & Garden Country Store is NOT going out of business! We are moving just down the road to the Hive & Garden farm. This move allows us to expand our vision and explore new ways to connect with our wonderful customers. As we make room for our next chapter, we're offering someone else the opportunity to bring their own dream to life in this special property! Featuring the warmth and character of a beautiful wood stove with a certified chimney, this inviting country-style space is ready for its next adventure. Recent Improvements & Features 2,316 square feet of commercial retail space Architectural roof installed in 2021 New split units New windows Newly remodeled bathroom New three-compartment commercial kitchen sink New 200-amp electrical service, panel, and meter Mop station One-bay garage Charming wood stove with certified chimney The Possibilities Are Endless! Keep the country-store charm or create something entirely new! This property would be perfect for: A charming country store or specialty market A cozy coffee shop or café An ice cream shop or dessert parlor A sandwich shop or small restaurant A boutique or gift shop A specialty retail business A unique destination business The existing kitchen setup provides a great starting point for a food-service concept. A grease trap and applicable permits and approvals would be needed for certain food-service uses. A Location with Opportunity! Enjoy the appeal of a small-town setting with little competition for many specialty retail and food-service concepts. Whether you've dreamed of owning a little country store, opening a coffee shop, serving up ice cream, or creating something completely your own, this property offers a wonderful foundation. Don't just buy a commercial building. Buy the opportunity to create something special! Come see the possibilities and imagine what your next business adventure could be! Hive & Garden isn't saying goodbye. We're simply making room for our next big adventure at The Farm! Investment highlights Newly remodeled Rocking chair front porch Ready for a new business Charming country store 2316 sq ft retail property Iron wood stove On the main road at a main intersection

Easley

1926 Anderson Highway, Easley
$512,000
20309329 MLS
Small-Town Charm, BIG Business Potential! 2,316 SF Commercial Property | Retail | Restaurant | Coffee Shop | Country Store A Little Country Charm with Endless Possibilities! Looking for a unique commercial property with character, charm, and opportunity? This 2,316-square-foot retail property offers the perfect blend of small-town charm and modern improvements! An Exciting New Chapter for Hive & Garden Country Store! Hive & Garden Country Store is NOT going out of business! We are moving just down the road to the Hive & Garden farm. This move allows us to expand our vision and explore new ways to connect with our wonderful customers. As we make room for our next chapter, we're offering someone else the opportunity to bring their own dream to life in this special property! Featuring the warmth and character of a beautiful wood stove with a certified chimney, this inviting country-style space is ready for its next adventure. Recent Improvements & Features 2,316 square feet of commercial retail space Architectural roof installed in 2021 New split units New windows Newly remodeled bathroom New three-compartment commercial kitchen sink New 200-amp electrical service, panel, and meter Mop station One-bay garage Charming wood stove with certified chimney The Possibilities Are Endless! Keep the country-store charm or create something entirely new! This property would be perfect for: A charming country store or specialty market A cozy coffee shop or café An ice cream shop or dessert parlor A sandwich shop or small restaurant A boutique or gift shop A specialty retail business A unique destination business The existing kitchen setup provides a great starting point for a food-service concept. A grease trap and applicable permits and approvals would be needed for certain food-service uses. A Location with Opportunity! Enjoy the appeal of a small-town setting with little competition for many specialty retail and food-service concepts. Whether you've dreamed of owning a little country store, opening a coffee shop, serving up ice cream, or creating something completely your own, this property offers a wonderful foundation. Don't just buy a commercial building. Buy the opportunity to create something special! Come see the possibilities and imagine what your next business adventure could be! Hive & Garden isn't saying goodbye. We're simply making room for our next big adventure at The Farm! Investment highlights Newly remodeled Rocking chair front porch Ready for a new business Charming country store 2316 sq ft retail property Iron wood stove On the main road at a main intersection

1926 Anderson Highway, Easley

1926 Anderson Highway, Easley
$512,000
1609120 MLS
Small-Town Charm, BIG Business Potential! 2,316 SF Commercial Property | Retail | Restaurant | Coffee Shop | Country Store A Little Country Charm with Endless Possibilities! Looking for a unique commercial property with character, charm, and opportunity? This 2,316-square-foot retail property offers the perfect blend of small-town charm and modern improvements! An Exciting New Chapter for Hive & Garden Country Store! Hive & Garden Country Store is NOT going out of business! We are moving just down the road to the Hive & Garden farm. This move allows us to expand our vision and explore new ways to connect with our wonderful customers. As we make room for our next chapter, we're offering someone else the opportunity to bring their own dream to life in this special property! Featuring the warmth and character of a beautiful wood stove with a certified chimney, this inviting country-style space is ready for its next adventure. Recent Improvements & Features 2,316 square feet of commercial retail space Architectural roof installed in 2021 New split units New windows Newly remodeled bathroom New three-compartment commercial kitchen sink New 200-amp electrical service, panel, and meter Mop station One-bay garage Charming wood stove with certified chimney The Possibilities Are Endless! Keep the country-store charm or create something entirely new! This property would be perfect for: A charming country store or specialty market A cozy coffee shop or café An ice cream shop or dessert parlor A sandwich shop or small restaurant A boutique or gift shop A specialty retail business A unique destination business The existing kitchen setup provides a great starting point for a food-service concept. A grease trap and applicable permits and approvals would be needed for certain food-service uses. A Location with Opportunity! Enjoy the appeal of a small-town setting with little competition for many specialty retail and food-service concepts. Whether you've dreamed of owning a little country store, opening a coffee shop, serving up ice cream, or creating something completely your own, this property offers a wonderful foundation. Don't just buy a commercial building. Buy the opportunity to create something special! Come see the possibilities and imagine what your next business adventure could be! Hive & Garden isn't saying goodbye. We're simply making room for our next big adventure at The Farm! Investment highlights Newly remodeled Rocking chair front porch Ready for a new business Charming country store 2316 sq ft retail property Iron wood stove On the main road at a main intersection

1926 Anderson Highway, Easley

393 Youngs Bend  Road, Kershaw
$1,625,000
11 Baths ⋅ 4442574 MLS
Exceptional Commercial Hospitality & Event Venue Opportunity | Approximately 30 Acres | Kershaw, SC A rare opportunity to acquire an extraordinary hospitality property with tremendous potential for commercial use. Situated on approximately 30 private acres in Kershaw, South Carolina, this expansive 10,000+ square-foot estate offers an exceptional opportunity for a bed and breakfast, event venue, corporate retreat, boutique hospitality destination, or other permitted business ventures. Conveniently located just minutes from Carolina Motorsports Park and positioned between historic Camden and Lancaster, the property offers both privacy and accessibility. The impressive estate features 8 bedrooms, 9 full bathrooms, and 2 half baths, with three full kitchens in the main residence and multiple laundry facilities. Its three distinct wings provide flexibility for guest accommodations, private suites, administrative offices, or separate operational spaces. A private in-law suite offers an additional garage and separate entrance, creating even more versatility for guest or staff accommodations. The property's extensive improvements include several additional structures, including an all-brick workshop, classic barn, and separate outbuilding. The grounds feature a beautifully appointed circular drive, elegant paver entrance, and stately port-cochère, creating an impressive arrival experience for guests and visitors. Outdoor amenities further enhance the property's hospitality potential. A heated swimming pool is accompanied by an impressive pool house featuring a full kitchen, full bathroom, wood-burning fireplace, and outdoor shower. A pull-through garage beneath the pool house provides additional functionality. Multiple screened porches and expansive outdoor spaces offer opportunities for gatherings, private events, and guest enjoyment. The approximately 30 acres of open and wooded land provide significant flexibility for additional outdoor amenities and potential business enhancements, subject to applicable approvals. Potential concepts include outdoor event spaces, equestrian activities, recreational offerings, gardens, and private retreat experiences. Recent Capital Improvements Include: New roof (2025) Six HVAC units, with several recently replaced between 2020 and 2025 Three tankless water heaters installed in 2020 Two additional 40-gallon electric water heaters Please note: The property's well pump is not currently operational. Whether you envision an upscale bed and breakfast, a distinctive event destination, a corporate retreat, or another hospitality-related venture, this property offers an exceptional combination of existing improvements, acreage, infrastructure, and location. Buyers must verify zoning, permits and ordinances. Opportunities of this scale and versatility are increasingly difficult to find. Explore the possibilities and bring your vision to this remarkable Kershaw County offering. Due to MLS photo limitations, contact your agent for an unbranded link featuring the complete photo collection. Buyer to independently verify permitted uses, applicable business licensing, occupancy requirements, utilities, and any necessary permits or approvals for their intended operation.

393 Youngs Bend Road, Kershaw

308 W Stone Avenue, Greenville
$660,000
1 Baths ⋅ 1609075 MLS
YOUR BUSINESS DESERVES A LOCATION LIKE THIS. Give your business a professional presence in an outstanding Greenville location with the visibility, convenience, and character that are increasingly hard to find. Set along high-traffic W Stone Avenue, this 1,380-square-foot commercial office combines a polished business setting with the inviting character of a Southern bungalow, complete with shaker siding and a covered front porch. Inside, you'll find a welcoming reception area and five offices, with one offering the flexibility to serve as an over size conference room. A dedicated break-room features a kitchenette with counters, cabinets, and sink, along with space for a refrigerator, and a washer and dryer hookup. The layout is well suited to a professional practice while providing room to make the space work for your business. Outside, 10 dedicated parking spaces provide an exceptional advantage for a five-office professional setting—plenty of room for your team and clients without the parking challenges often associated with a downtown-adjacent location. Existing signage adds visibility along W Stone Avenue, while downtown Greenville, Greenlink transit, and the downtown trolley are all conveniently nearby. Zoned Commercial/Office and currently configured for professional office use, this is an opportunity to own a distinctive business address in one of Greenville's most desirable locations. If your business has reached the point where location, visibility, parking, and professional presence matter, take a closer look at 308 W Stone Avenue.

308 W Stone Avenue, Greenville

303 Beta Street, Anderson
$375,000
20309277 MLS
BUILT FROM THE GROUND UP WITH PURPOSE, PRECISION, AND POSSIBILITIES! This impressive 30x80 commercial grade metal building offers 2,400 square feet of heated and cooled space situated on two lots, providing an exceptional opportunity for business owners, entrepreneurs, investors, or automotive enthusiasts. Every inch of this property was thoughtfully planned and meticulously constructed with an extraordinary level of attention to detail, beginning well below the surface. The foundation was engineered for strength and longevity with additional clay, extensive grading, and compaction testing. The reinforced concrete slab features a minimum of 7 inches of 4,000 PSI concrete with fiber strands, wire, and rebar, complemented by 2 foot turndown footings and a 12 foot concrete parking apron. Inside, the building features three spacious bays, a heated and cooled office, and 1.5 bathrooms, including a full bath that opens the door to additional possibilities. Conveniently located directly across from the historic Equinox Mill, which is slated for redevelopment, this property is positioned to benefit from the area's potential revitalization and an expanding customer base. Whether you envision an automotive repair business, specialty workshop, contractor headquarters, or a combination of business and personal space, the opportunities are abundant. The office and full bath also offer potential for conversion into studio style living quarters, subject to applicable zoning and approvals, creating the possibility of living where you work while building your business and your future. Built with intention, positioned for opportunity, and ready for its next chapter!

303 Beta Street, Anderson

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The Listings data contained on this website comes from various participants of The Multiple Listing Service of Greenville, SC, Inc. Internet Data Exchange. IDX information is provided exclusively for consumers' personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. The properties displayed may not be all the properties available. All information provided is deemed reliable but is not guaranteed. © 2026 Greater Greenville Association of REALTORS®. All Rights Reserved. Last Updated

“ Based on information submitted to the MLS GRID as of . All data is obtained from various sources and may not have been verified by broker or MLS GRID. Supplied Open House Information is subject to change without notice. All information should be independently reviewed and verified for accuracy. Some IDX listings have been excluded from this website. Properties may or may not be listed by the office/agent presenting the information © 2026 Canopy MLS as distributed by MLS GRID”

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