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Commercial Real Estate for Sale in Upstate SC

Commercial activity in the Upstate follows the interstates. I-85 between Greenville and Spartanburg carries the industrial and distribution demand, with BMW and its supplier network anchoring most of it; retail and office concentrate around the two downtowns and the Highway 9 and Fairview Road corridors.

Commercial runs on different diligence than residential — zoning and permitted use, environmental history, existing leases and their remaining terms, and what a building can actually be converted to. Tell us what you are trying to do and we will scope the search.

Commercial Listings

$324,900
20305364 MLS
Prime Main St visibility meets character and versatility! Located in the heart of Williamston with approximately 11,200 vehicles passing daily, this attractive commercial property offers an ideal setting for a professional office, boutique, bakery, jewelry store or other business opportunity. The interior features four private offices, beautifully refinished hardwood floors, a kitchen, breakroom, and bathroom, while the inviting covered front porch adds distinctive curb appeal. Zoned RC and surrounded by established businesses, the property is less than a mile from Mineral Spring Park and positioned in a growing community with new residential development underway. Bring your business to Main Street and take advantage of the visibility, location and flexibility this property offers! Approximate room sizes, if important to buyer please have buyer verify: Lobby: 18x13, Office (1) 14x11, Office (2) 11x11, Office (3) 13x11, Office (4) 16x11, Bathroom 11x5, Breakroom 14x11, Back Porch 12x10.

402 W Main Street, Williamston
$1,250,000
340929 MLS
Versatile Commercial Property with Excellent Visibility & High-Traffic Exposure Prime commercial opportunity at 118 Rainbow Lake Road in Boiling Springs, offering excellent visibility along a high-traffic area and a flexible layout suitable for a variety of business uses. Currently operating as a car lot, this well-maintained property was built in 2018 and sits on approximately 0.76 acres. The spacious front office features LVP flooring throughout and includes six private offices, reception areas, a kitchen, and separate public his and her restrooms. Additional features include public parking and a two-bay garage, making the property well suited for continued automotive use, an auto mechanic or service business, office space, or a combination of uses. With a functional layout, ample parking, garage space, and a highly visible location, this property offers an excellent opportunity for an owner-user or investor looking for a versatile commercial property in a growing Boiling Springs area.

Boiling Springs
$3,500,000
11 Baths ⋅ 4417571 MLS
Welcome to Wildberry Lodge, an extraordinary mountain estate and established Bed & Breakfast opportunity in Leicester, NC, where breathtaking long-range mountain views, privacy, and unforgettable experiences come together in the heart of Western North Carolina. Surrounded by natural beauty yet convenient to Asheville, this one-of-a-kind property offers the rare combination of a luxury mountain retreat, equestrian potential, guest accommodations, and income-producing possibilities. The impressive main lodge is designed for gathering, relaxing, and hosting, with multiple private en-suite bedrooms, expansive living and entertaining spaces, stone wood-burning fireplaces, a game room with bar, library, wine cellar, and inviting spaces throughout. The spacious BlackBerry primary suite feels like its own private retreat with a stone fireplace, kitchenette, luxurious bath, walk-in closet, and private porch overlooking the mountain setting. A separate two-level guest house dramatically expands the possibilities. With kitchens, living spaces, fireplaces, private accommodations, and its own HVAC zoning, it is ideal for extended family, guests, vacation rental use, or additional Bed & Breakfast accommodations. Step outside and the property becomes an experience of its own. Soak in the hot tub beneath the mountain sky, gather around the outdoor living areas, explore private walking trails, or escape to the property’s charming tipi tucked into the natural surroundings. The expansive mountain views are truly spectacular, creating a backdrop that changes with every season. For equestrian buyers, the property offers a high-quality Morton horse barn, ample space for horses, and the opportunity to create an exceptional private mountain equestrian retreat. Additional storage and utility buildings provide even more flexibility. Whether you envision continuing Wildberry Lodge as a Western North Carolina Bed & Breakfast, creating a luxury vacation retreat, establishing an equestrian estate, hosting family and friends, or simply enjoying an extraordinary private mountain sanctuary, the possibilities here are remarkable. Wildberry Lodge isn’t simply a property—it’s a destination. A place to wake up to mountain views, gather around a roaring stone fireplace, ride horses through the mountain air, soak beneath the stars, welcome guests from around the world, and experience the lifestyle that makes the North Carolina mountains so special. Also listed as Residential MLS# 4415427.

135 Potato Branch Road, Leicester
$625,000
2 Baths ⋅ 4417524 MLS
Commercial/Residential/Multi-family units (hybrid-investment) potential!- Come ring your bell- seriously, it has a bell! Spruce Pine NC -located in a prime business location w/200ft. of US Hwy. 19-E frontage & high visibility on the main thoroughfare between Asheville & Boone. Situated on 1.85 level acres, paved drive & parking with NO ZONING! NO RESTRICTIONS! NO CITY TAXES! Featuring main hall, kitchen, meeting rooms, bathrooms & newly waterproofed basement w/warranty. City Water/Sewer & Natural Gas available. Septic & well in place for home. Top market area known for Outdoor Recreation, Adventure, Tourism, Retirement, Artist & Galleries; The Opportunities are endless: Restaurant, Commercial Trucking Lot, Church, Studio, Fitness/Martial Arts Center, Coffee/Bakery Shop, Multi-family Units, Pet Daycare/Grooming, Hair Salon, Vigilante Lair etc.. 3 min. to downtown, 30 min. to Lake James & I-40, 40 min. to Boone, 50 min. to Asheville, 2hrs from Charlotte.

12348 Us Hwy 19 E Highway, Spruce Pine
$2,395,000
4410029 MLS
Exceptional Class A building with a rare blend of finished office, studio, and warehouse space. 50 Fisk Drive consists of 10,612 SF on 1.09 acres in the heart of Arden's business/industrial corridor, with easy access to Hendersonville Road, Long Shoals Road, and Airport Road. The lower level features a striking lobby with floor-to-ceiling glass wall entrance and vaulted ceilings, four private offices (one with private bathroom/shower), a kitchen/break room, three bathrooms, storage and file/IT rooms, a flexible lounge area convertible to additional offices, and two sound studios (±1,350 SF) that could be adaptable to office or warehouse use. Additionally, there is 689 SF of warehouse space on the main level with ±18' ceilings and covered loading dock/drive-in access (10x12' doors). The 2nd floor includes five private offices, a large shared work area (±986 SF), a glass-walled conference room (419 SF), two additional bathrooms, and a ±1,800 SF mezzanine offering additional storage and access to the warehouse. A peaceful wooded setting adds a rare quality to this property, which is still in immediate proximity larger industrial facilities. I-26 is just minutes away for interstate connectivity to Asheville and Hendersonville. Building systems include a new 3-ton HVAC unit (installed July 2026, other units quarterly-maintained), a 2015 roof (quarterly-maintained), natural gas, city water/sewer, 240V power, and ADT security. Recently-surfaced parking lot accommodates an estimated 35 vehicles. The building is not fire-sprinkled and has no elevator. ±10,612 SF Class A office/warehouse building on 1.09 acres in Arden, NC Offered at $2,395,000 ($225/SF)—to be delivered vacant Immaculate condition throughout, with Class A finishes Masonry construction with striking two-story glass wall entrance Flexible layout of private offices across two floors 689 SF of warehouse space with ±18' ceilings Two roll-up 10'x12' loading bay doors with covered canopy and paved loading apron ±1,800 SF of additional mezzanine space New 3-ton HVAC unit (installed July 2026); other HVAC units and roof (2015) maintained quarterly Natural gas, city water/sewer, 240V power, and ADT security system in place Newly-surfaced parking lot with an estimated 35 spaces (±3/1,000 SF parking ratio) Quiet, wooded setting Central Arden location Approximately 3 miles (6–8 minutes) from Asheville Regional Airport (AVL) Zoned EMP (Employment District) Note: building is not fire-sprinkled, no backup generator, no elevator

50 Fisk Drive, Arden
$1,750,000
4417486 MLS
Commercial property available for sale in Charlotte’s highly desirable Elizabeth neighborhood, offering exceptional proximity to Uptown Charlotte, Plaza Midwood, and direct access to public transit. Well- suited for office, retail, or investment use under N2-B zoning, the building features 3,233 SF with several value-add opportunities. Positioned in a vibrant, highly walkable area surrounded by local dining and boutique retail, the property sits directly adjacent to the CityLYNX Gold Line streetcar with a transit stop located less than 50 feet from the front door. Renovated in 2025.

610 Hawthorne Lane, Charlotte
$3,295,000
4417413 MLS
Redevelopment / Repositioning Opportunity Strategically positioned commercial property presenting an opportunity for an investor, developer, or owner-user to reposition or redevelop the existing site to maximize its income-producing potential. The property currently includes multiple tenant spaces, providing existing occupancy while allowing flexibility for future redevelopment, reconfiguration, or repositioning. Potential permitted uses may include retail/showroom, professional and business services, office, medical/dental, restaurant/food service, personal services, automotive-oriented businesses, and certain vehicle repair/service uses, subject to applicable Charlotte Unified Development Ordinance (UDO) requirements and site-specific conditions. Automotive uses may offer particularly attractive repositioning potential. Charlotte's CG zoning framework can accommodate certain vehicle-repair and automotive service uses, subject to applicable conditions, which may include enclosed repair activities, storage limitations, landscaping, screening, and other UDO requirements. The property's existing configuration and location provide an opportunity to increase occupancy, reposition the tenant mix, renovate the existing improvements, or pursue a redevelopment strategy designed to enhance long-term value and income potential

3108 E Independence Boulevard, Charlotte
$45,000
20305298 MLS
Prime commercial corner opportunity at the intersection of Highway 29 Bypass and Dostak Drive, positioned in a high traffic area surrounded by established commercial businesses and directly adjacent to the South Carolina Department of Motor Vehicles. This highly visible property offers excellent accessibility and a versatile setting for a variety of potential uses, including a new business location, professional or service related development, or possible duplex/multifamily development, subject to applicable zoning and approvals. Conveniently located just minutes from Downtown Anderson, the property offers easy access to two major thoroughfares serving Anderson County, along with a direct route to Interstate 85. Whether you are looking for a strategic commercial location, an investment opportunity, or a site with future development potential, this corner lot delivers visibility, convenience, and possibilities.

Lot 18 HWY 29 + Dostak Drive, Anderson
$1,371,000
4412969 MLS
Introducing a prime investment opportunity in the heart of Hendersonville, NC. This historic 5,656 SF building, originally constructed in 1900 and stylishly renovated in 2008, offers an exceptional space for office or office building use. Zoned within the Central Business District, the property's strategic location provides businesses with unparalleled visibility and access. With its rich heritage, modern updates, and ideal positioning, this property is poised to captivate investors seeking a distinguished commercial asset in the thriving Hendersonville area. Don't miss the chance to make this prestigious address the cornerstone of your investment portfolio. 5,656 SF historic building 7 Parking Spaces New Roof Main Street Frontage Renovated in 2008 Zoned Central Business District Prime Hendersonville location

337 N Main Street, Hendersonville
$500,000
4417095 MLS
Commercial opportunity on Highway 29 at the corner of Concord Farms! This nearly one-acre vacant lot is positioned in a busy economic hub, approximately 2.5 miles from Charlotte Motor Speedway and within five miles of Concord Mills. Commercial zoning and no minimum building square-footage requirement offer flexibility for a variety of potential uses, with a maximum building size of 32,060 square feet. A well and septic system will need to be installed. Buyer and buyer’s agent should verify zoning, permitted uses, building requirements, utilities, well and septic feasibility, and all development regulations with the appropriate authorities.

2701 Concord Farms Road, Concord
$787,500
4417193 MLS
Fully operational daycare facility licensed for a total occupancy of up to 60 children and staff, with capacity established by county regulations and the existing septic system. This turnkey opportunity includes all furniture, fixtures, equipment, classroom materials, playground equipment, and other contents located both inside and outside the building. The facility is designed for childcare operations and offers an excellent opportunity for a childcare provider or business owner seeking a move-in-ready facility. Conveniently located in Shelby with ample parking and easy access. Buyer and buyer’s agent responsible for verifying zoning, licensing requirements, occupancy limits, and intended use. Do not disturb staff, children, or ongoing business operations. All showings by appointment only through the listing agent.

1139 Poplar Springs Church Road, Shelby
$2,000,000
1601586 MLS
22,850± SF Heated & Cooled Commercial Property on 2.13± Acres Located approximately six miles from Downtown Greenville, this property offers approximately 22,850 square feet of heated and cooled commercial space in an unzoned, unrestricted area of unincorporated Pickens County. Three-phase power is available, and owner financing may be available to qualified buyers. Originally designed for school use, the building was later used as a church and most recently operated as a wedding and event venue. The approximately 15,625 SF main level includes an 80' × 105' high-ceiling open space, totaling 8,400 SF. Originally designed as a gymnasium, this area later served as a sanctuary and event space. The remaining 7,225 SF on the main level includes eight classrooms or offices, men’s and women’s restrooms, a warming kitchen, and an adjoining cafeteria-style space. An additional 7,225 SF upstairs contains 15 classrooms or offices. The 125' × 125' building provides a total of approximately 14,450 SF of office, classroom, kitchen, restroom, and support space, in addition to the 8,400 SF open main room. Approximately 140 total parking spaces are available, including roughly 40 spaces on the property and access to 100 additional spaces through a recorded shared-parking agreement with the neighboring church. Property Highlights * 22,850± SF heated and cooled building * 2.13± acres * Approximately six miles from Downtown Greenville * Unzoned and unrestricted * Three-phase power available * 15,625± SF main level * 80' × 105' high-ceiling open room * Approximately 23 classrooms or offices * Approximately 140 total parking spaces available * Warming kitchen and cafeteria-style space * Owner financing available

3825 Saluda Dam Road, Easley
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