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Commercial Real Estate for Sale in Upstate SC

Commercial activity in the Upstate follows the interstates. I-85 between Greenville and Spartanburg carries the industrial and distribution demand, with BMW and its supplier network anchoring most of it; retail and office concentrate around the two downtowns and the Highway 9 and Fairview Road corridors.

Commercial runs on different diligence than residential — zoning and permitted use, environmental history, existing leases and their remaining terms, and what a building can actually be converted to. Tell us what you are trying to do and we will scope the search.

Commercial Listings

$350,000
4415415 MLS
Zoned GB in the county. Ready to start your business. Lynwood Dr is convenient to downtown and Hwy 200. Over 300 ft of road frontage. Total of 6.11 acres. Can be sold in 2 parcels, one at 5.65 and the other almost 1/2 acre. Property can be subdivided. Call now for your tour of the property!

1670 Lynwood Drive, Lancaster
$10,900,000
4405718 MLS
This well-maintained industrial facility offers a total of 87,000 square feet, consisting of approximately 75,000 SF of warehouse space and 12,000 SF of office area. Originally built in 1988, the property was expanded by 35,000 SF in 2011, enhancing its functionality and increasing its capacity for a variety of industrial and distribution uses. Strategically positioned along Cane Creek Road in Fletcher, NC, the property provides convenient access to major transportation corridors, a strong regional workforce, and Asheville Regional Airport. The site’s efficient layout and clear-span warehouse design offer excellent flexibility for manufacturing, warehousing, and logistics operations.

280 Cane Creek Road, Fletcher
$1
4415432 MLS
Bring your vision to this unique commercial property in the heart of Downtown York! Situated on approximately 0.10± acres and zoned B-1 Central Business District, the property offers an existing commercial building ready for renovation and repositioning. The front portion was most recently utilized as a tax office, while the rear portion formerly operated as a restaurant, offering an interesting layout and plenty of possibilities for an investor, entrepreneur or owner-user. Located on N. Roosevelt Street beside City Hall and within steps of the York Public Library, the property is surrounded by downtown businesses, public amenities and community activity. The property is being offered as an opportunity to reimagine an existing downtown commercial space for its next chapter. Potential uses may include retail, office, restaurant, service and more! Property will be sold by Online Auction through 12:00 PM on Wed. October 7th, 2026. The purchaser will have up to 45 days to close. Please Note: This is NOT a distressed or foreclosed property. The owner has simply chosen the online auction method as the preferred way to market and sell the property. Property is being sold subject to the auction terms and conditions. See full terms for complete details. ADDITIONAL OPPORTUNITY: The adjoining property at 4 N. Roosevelt St. is also being offered for sale.

6 Roosevelt N Street, York
$1
4415387 MLS
Bring your vision to this 468± SF brick building on 0.11± acres in the heart of Downtown York. Zoned B-1 Central Business District, this property offers a unique opportunity to renovate and reposition a small commercial property in an exceptional downtown location. Situated on N. Roosevelt Street beside the York Public Library and just steps from York City Hall, Floyd Allison Memorial Park and the historic Southern Railway Depot, the property is surrounded by downtown businesses, public amenities and community activity. The compact footprint could lend itself to a creative boutique retail concept, studio, specialty shop, professional space and more. Whether you're an investor looking for a redevelopment project or an entrepreneur searching for an affordable downtown presence, this property offers plenty of upside. Property will be sold by Online Auction through 12:00 PM on Wed. October 7th, 2026. The purchaser will have up to 45 days to close. Please Note: This is NOT a distressed or foreclosed property. The owner has simply chosen the online auction method as the preferred way to market and sell the property. Property is being sold subject to the auction terms and conditions. See full terms for complete details. ADDITIONAL OPPORTUNITY: The adjoining property at 6 N. Roosevelt St. is also being offered for sale.

4 Roosevelt N Street, York
$399,999
20305131 MLS
Position your business for success at Heritage Station, 1510 Blue Ridge Blvd, Suite 103 in Seneca, SC. This main level 1,815 sq. ft. professional commercial space combines a polished business setting, functional layout and convenient access located at the right corner of this Plaza facing Blue Ridge Blvd. The suite features a spacious reception and waiting area or showroom, three private offices- one formerly used as a large conference meeting room, two restrooms, a janitor’s closet room, room at the rear corner area for break area and generous hallway space that provides an easy flow throughout the property. A rear exit offers additional access and the potential for a convenient employee entrance, while ample on-site parking helps accommodate both clients and staff. The versatile layout is well suited for a variety of professional uses, including financial services, insurance, legal, medical-related, administrative, consulting, or other office-based businesses. Existing furnishings and select artwork may also convey, providing an opportunity for a buyer looking for a more turnkey setup. Suite 103 could also be used for retail in this 11 suite plaza. Also available for lease at $ 3150 per month. Located along Blue Ridge Blvd near Bountyland Road and Keowee School Road, Heritage Station offers convenient access to Seneca, Walhalla, and surrounding Oconee County. Whether you're relocating an established business, expanding your operation, or purchasing commercial space instead of leasing, Suite 103 offers the location, professional appearance, and functional layout to make a strong impression from day one. Schedule your private showing and see what Heritage Station Suite 103 can offer your business. Formerly the Edward Jones Suite purchased at new construction.

1510 Blue Ridge Boulevard Unit 103, Seneca
$35,000
340726 MLS
Always wanted to live in a Fire House? Here is your chance. Good bones to convert in however you want. There is no fire pole, but this piece of history, the Whitney Fire House built in 1930 could be yours. Or maybe convert to a duplex. What ideas do you have, lets talk.

Spartanburg
$799,000
1 Baths ⋅ 1601152 MLS
Great opportunity! 5.07 acres, approx. 3+- acres fenced, balance in woods. Property fronts Providence Church Rd. Warehouse building is as follows: Enclosed middle 75'wide x150' long. Building contains one office, one bathroom 8'x40'. Bathroom and office are air conditioned. Building has 4 - 15' roll up doors (one per side), 3 - personal doors (one on front and one on each side). Building also has covered, open parking/storage/work space on each side. Areas are 25' deep and approx. 100' long. columns are spaced approx. 25' apart. Concrete is re-enforced for truck traffic or heavy manufacturing equipment. Building is well insulated and in excellent condition. There are 2 outbuildings on the property, they do not convey.

1105 Providence Church Road, Anderson
$2,950,000
4415322 MLS
12.9 AC Site at the I-26 Columbus NC exit. Interstate frontage. Excellent commercial site for multi-family, hotel, restaurant, fast food, gas station, C-store, truck stop, retail center, etc... on main commercial corridor in Columbus NC. Close to Wendy's, Waffle House, Advance Auto Parts, State Employee's Credit Union, CVS, etc... Call broker to discuss options.

99999 Weaver Street, Columbus
$3,699,000
4407768 MLS
Recently renovated medical space. Great location in Asheville's medical district on a main north to south thoroughfare.

275 Mcdowell Street, Asheville
$460,000
4415151 MLS
Excellent opportunity to acquire approximately 2.28 acres in the established Coffey Creek Business Center at 3350 Green Park Circle, in Charlotte, strategically positioned in the corridor near major interstates: I-77, I-85, and near CLT-Douglas Airport. The property is positioned for commercial/industrial development and offers an attractive opportunity for an investor, owner-user, or developer seeking land in a strategic Charlotte location. The site features a paved road, no HOA, and convenient access to major transportation routes. It's zoned B-D (CD), providing lots of opportunities. The property offers flexibility for a range of potential uses, including warehouse, distribution, manufacturing, or other commercial applications, subject to zoning and due diligence. An excellent opportunity to secure well-located development land in one of Charlotte's active business corridors. Great topography. Buyer to independently verify zoning, permitted uses, utilities, site conditions, and development requirements.

3350 Green Park Circle, Charlotte
$375,000
20305093 MLS
Prime commercial development opportunity on approximately 1.06 acres along Pearman Dairy Road/ SC-28 Bypass, directly across from Westside High School. Approved development plans are in place for two approximately 4,200-square-foot commercial buildings, totaling approximately 8,400 square feet. The plans provide flexibility for flex space, office/warehouse, contractor, service, and other commercial uses, subject to applicable requirements. One of the buildings also includes a loading dock in the approved plans, enhancing its functionality for businesses requiring shipping, receiving, or material handling. The property offers approximately 21,300 Average Annual Daily Traffic (AADT),This provides substantial visibility and exposure for future occupants. With approved plans, a high-traffic location, and a versatile commercial layout, this site presents an attractive opportunity for an owner-user, investor, or developer seeking a ready-to-advance commercial project in the Anderson market.

821A + 821B Pearman Dairy Road, Anderson
$430,000
20305024 MLS
Rare opportunity in the heart of Downtown Anderson! This approximately 6,400 sq. ft. commercial property sits on approximately 0.32 acres and offers exceptional potential for redevelopment, investment, or owner-occupancy. The building features approximately 1,600 sq. ft. in the front single-story section with a two-story rear section offering approximately 2,400 sq. ft. on each level. Property features include 3-phase power, concrete first floors, city sewer, and a newer roof over the single-story section. Currently in shell condition, the property provides a flexible canvas for a variety of commercial concepts, including retail, office, showroom, studio, contractor, flex, or mixed-use opportunities. Potential parking is available in the front, with a sizable rear area offering additional parking or site-improvement possibilities. Located in the historic downtown Anderson area with convenient access to shopping, dining, businesses, and downtown amenities. Bring your vision and take advantage of this unique redevelopment opportunity.

215 W Church Street, Anderson
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“ Based on information submitted to the MLS GRID as of . All data is obtained from various sources and may not have been verified by broker or MLS GRID. Supplied Open House Information is subject to change without notice. All information should be independently reviewed and verified for accuracy. Some IDX listings have been excluded from this website. Properties may or may not be listed by the office/agent presenting the information © 2026 Canopy MLS as distributed by MLS GRID”

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